Microsoft Office has a number of features that assist with the creation of accessible files. See the links in the navigation menu for detailed instructions from Microsoft on creating accessible Word, Excel and PowerPoint files. In addition, a "Save as Daisy" add-in, which allows you to create documents that are readable in the DAISY Talking Book format, is available for Word (see below for detailed information).
The "Save as DAISY" add-in for Word allows documents to be saved in Daisy XML, which can then be easily converted into DAISY Digital Talking Book format.
Installation is a two-step process. First, you must download the Open XML to Daisy XML translator (see the Save as Daisy project page to select the version appropriate to your Office installation). Next, you must download a DAISY reader, such as AMIS (a free and open-source solution developed by the DAISY consortium) in order to check/listen to your work. A list of available playback tools can be found through the DAISY Consortium.
Information on getting started with the "Save as DAISY" add-in can be found at the Microsoft Office Help Site under Using the Save as Daisy add-in. Additionally, the "Save as Daisy Getting Started" document (part of the add-in install package) is extremely helpful in explaining how to use the product.